Selenium (from SelenoExcell® High Selenium Yeast) (Saccharomyces cerevisiae)
50 mcg
90%
Molybdenum (from molybdenum glycinate chelate)
50 mcg
110%
N-Acetylcysteine (NAC)
600 mg
†
Top Medical Research Studies
8
Selenium aids hair loss in PCOS
Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome.
We conducted a randomized double-blind, placebo-controlled trial to explore how selenium supplementation may influence hair loss among women with polycystic ovary syndrome (PCOS). In the study, 64 women aged 18-40 received either 200 μg of selenium daily or a placebo for eight weeks.
After the treatment period, we noticed a significant improvement in hair-related issues for those taking selenium. Specifically, alopecia rates dropped from 40.6% in the selenium group to just 9.4% in the placebo group, showing a strong positive effect of the supplement on hair loss. Acne also improved, with a reduction from 46.9% to 12.5%.
Furthermore, women who took selenium supplements exhibited decreased levels of dehydroepiandrosterone (DHEA), hirsutism, and markers of inflammation and oxidative stress. However, it’s important to note that selenium did not show significant effects on some hormonal profiles and other biomarkers. Overall, our findings suggest that selenium can be beneficial for women with PCOS, particularly regarding hair loss and related symptoms.
We explored a novel approach to treat androgenetic alopecia (AGA) using microneedles that deliver selenium nanoparticles. The study designed a biocomposite patch to improve the environment around hair follicles by enhancing blood flow and reducing inflammation.
When tested on mice, this microneedle system showed promise in boosting hair density and enlarging hair follicles. However, while the results are encouraging, further research is needed to confirm its effectiveness in humans.
Read More
8
Selenium supplementation may help hair loss
Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy.
We examined how selenium supplementation influences hair loss in women undergoing chemotherapy for ovarian cancer. This study involved 31 patients who received 200 micrograms of selenium daily.
Over three months, we noticed significant improvements: hair loss decreased, alongside reductions in discomfort and fatigue. While selenium levels in patients' hair didn't increase markedly after the first month, serum levels rose significantly.
Ultimately, selenium appears beneficial as a supportive treatment in managing hair loss during chemotherapy.
Read More
Most Useful Reviews
9
Hair loss reduced
2 people found this helpful
I have been taking biotin for several weeks, which has significantly reduced my hair loss. I have more energy, and my mood has stabilised.
Read More
9
Good for hair loss
I recommend this product; it offers good value and quality for combating hair loss.
Read More
7.5
Hair loss ceased
I started taking this product in early 2021, having envied my colleague. My hair loss has stopped, though I'm unsure how much credit it deserves, as I engage in various hair care practices.
We explored a novel approach to treat androgenetic alopecia (AGA) using microneedles that deliver selenium nanoparticles. The study designed a biocomposite patch to improve the environment around hair follicles by enhancing blood flow and reducing inflammation.
When tested on mice, this microneedle system showed promise in boosting hair density and enlarging hair follicles. However, while the results are encouraging, further research is needed to confirm its effectiveness in humans.
Read More
8
Selenium may aid hair loss treatments
Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study.
We conducted a thorough investigation into the effectiveness of a novel oral supplement containing selenium, among other ingredients, in addressing hair loss conditions like androgenetic alopecia (AGA) and telogen effluvium (TE). Our study involved 83 participants who were divided into two groups: one received the supplement alongside their prescribed treatments, while the other received only the treatments.
Over 12 weeks, we assessed the outcomes primarily through a global assessment score to see how much improvement, if any, participants experienced. Interestingly, we found that the supplement—rich in selenium, amino acids, and hydrolyzed collagen—enhanced the results for those undergoing anti-hair loss therapies.
In essence, the inclusion of selenium in this combination supplement appears to positively influence the effectiveness of standard treatments for hair loss. While our study was promising, it’s worth noting that deriving individual results for selenium alone is complicated since it was combined with other beneficial components.
Read More
8
Selenium aids hair loss in PCOS
Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome.
We conducted a randomized double-blind, placebo-controlled trial to explore how selenium supplementation may influence hair loss among women with polycystic ovary syndrome (PCOS). In the study, 64 women aged 18-40 received either 200 μg of selenium daily or a placebo for eight weeks.
After the treatment period, we noticed a significant improvement in hair-related issues for those taking selenium. Specifically, alopecia rates dropped from 40.6% in the selenium group to just 9.4% in the placebo group, showing a strong positive effect of the supplement on hair loss. Acne also improved, with a reduction from 46.9% to 12.5%.
Furthermore, women who took selenium supplements exhibited decreased levels of dehydroepiandrosterone (DHEA), hirsutism, and markers of inflammation and oxidative stress. However, it’s important to note that selenium did not show significant effects on some hormonal profiles and other biomarkers. Overall, our findings suggest that selenium can be beneficial for women with PCOS, particularly regarding hair loss and related symptoms.
Read More
8
Selenium supplementation may help hair loss
Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy.
We examined how selenium supplementation influences hair loss in women undergoing chemotherapy for ovarian cancer. This study involved 31 patients who received 200 micrograms of selenium daily.
Over three months, we noticed significant improvements: hair loss decreased, alongside reductions in discomfort and fatigue. While selenium levels in patients' hair didn't increase markedly after the first month, serum levels rose significantly.
Ultimately, selenium appears beneficial as a supportive treatment in managing hair loss during chemotherapy.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8
All Reviews
Positive Reviews
Negative Reviews
9
Hair loss reduced
2 people found this helpful
I have been taking biotin for several weeks, which has significantly reduced my hair loss. I have more energy, and my mood has stabilised.
Read More
9
Good for hair loss
I recommend this product; it offers good value and quality for combating hair loss.
Read More
7.5
Hair loss ceased
I started taking this product in early 2021, having envied my colleague. My hair loss has stopped, though I'm unsure how much credit it deserves, as I engage in various hair care practices.
Read More
6
Thicker hair observed
15 people found this helpful
I've been taking biotin, vitamin C, and lactic acid bacteria. After six months, I've noticed thicker hair in areas affected by hair loss, which had previously been sparse.
Read More
7.5
Decreased hair loss
3 people found this helpful
I liked this product; it has helped with sputum discharge in chronic bronchitis, and as a bonus, my hair loss has decreased.
Hair loss, also known as alopecia, is a common condition that affects both men and women, characterized by the thinning or complete loss of hair from the scalp or other areas of the body. It can occur due to various factors, including genetics, hormonal changes, medical conditions, and environmental factors. The most prevalent type of hair loss is androgenetic alopecia, often referred to as male or female pattern baldness, which typically results in a receding hairline or thinning crown in men and overall thinning in women.
In addition to genetic predisposition, hair loss can be triggered by stress, poor diet, certain medications, and underlying health issues such as thyroid disorders or autoimmune diseases. There are various treatment options available, ranging from over-the-counter products like minoxidil to prescription medications and hair restoration procedures, depending on the severity and cause of hair loss. It's crucial to consult with a healthcare professional to determine the most appropriate treatment plan tailored to individual needs and conditions.
N-Acetyl Cysteine (NAC) is a modified form of the amino acid cysteine, known for its role as a powerful antioxidant and mucolytic agent. It has been widely used as a dietary supplement for various health benefits, including supporting respiratory health, detoxification, and enhancing overall immune function. NAC is particularly recognized for its ability to replenish glutathione, one of the body's most important antioxidants, which helps combat oxidative stress and protect cells from damage.
In addition to its antioxidant properties, N-Acetyl Cysteine is commonly leveraged in a clinical setting for its effectiveness in treating acetaminophen (Tylenol) overdoses, as it aids in restoring depleted glutathione levels, thus preventing liver damage. It can also be beneficial for individuals with chronic respiratory conditions, such as COPD or cystic fibrosis, as it helps in thinning mucus, making it easier to expel. While NAC is generally considered safe for most people, it’s important to consult a healthcare professional before starting any new supplement, particularly for those with pre-existing conditions or those already on medication.
Based on user reviews, the timeline for seeing results from this supplement can vary. Some users report noticing significant improvements in hair loss within a few weeks of starting the regimen. For instance, one reviewer mentioned that after several weeks of taking biotin, they experienced a substantial reduction in hair loss and improved energy levels Read Review. Others suggest that more considerable changes, such as achieving thicker hair, may take longer, with one user indicating they observed improvements after six months of consistent use Read Review.
Overall, while some users see benefits relatively quickly, others note that a commitment of several months may be needed before witnessing significant results. Factors such as unique hair care practices and overall health may also influence the effectiveness and timeframe of this supplement on hair loss. It's essential to maintain consistent usage for the best chance of positive results, which aligns with several user experiences shared in the reviews.
The role of selenium as a supplement for hair loss is supported by scientific research, revealing promising effects in various contexts. A study investigating an oral supplement rich in selenium alongside other beneficial components demonstrated an enhancement of hair loss treatment outcomes in participants with conditions such as androgenetic alopecia and telogen effluvium [1]. Additionally, a randomized controlled trial showed significant improvements in hair-related issues among women with polycystic ovary syndrome (PCOS) who supplemented with selenium. The results indicated a reduction in alopecia rates from 40.6% to 9.4%, underscoring the potential of selenium to effectively mitigate hair loss [2].
Other studies have also explored innovative delivery methods for selenium, such as microneedles, which improved hair density and follicle health in animal models [3]. Furthermore, selenium supplementation has been noted as beneficial for women undergoing chemotherapy, aiding in reducing hair loss and associated symptoms [4]. Collectively, these findings suggest that selenium can be a valuable component in the formulation of supplements aimed at addressing hair loss, although individual results may vary and further research is warranted to clarify its optimal application.
Based on user reviews, individuals report a variety of improvements concerning hair loss and overall well-being after incorporating biotin into their routines. A notable number of users have shared that they experienced a significant decrease in hair loss after just a few weeks of taking the supplement. For example, one user mentioned a substantial reduction in hair loss, along with increased energy and mood stabilization after a few weeks of use Read Review. Others, like a reviewer who started their regimen in early 2021, noted that their hair loss has stopped, although they acknowledged the possible influence of their additional hair care practices Read Review.
Additionally, some users report more long-term changes, such as a reviewer who observed thicker hair after six months of consistent biotin intake combined with other supplements Read Review. Interestingly, other anecdotal experiences indicate that while biotin can aid in managing hair loss, some users have also noticed improvements in unrelated symptoms, such as a reduction in sputum discharge in chronic bronchitis alongside decreased hair loss Read Review. However, it's important to note that results can vary greatly from person to person, and factors like individual health and concurrent treatments may greatly influence outcomes.
Based on user reviews, there is considerable discussion regarding the combination of this supplement with other products for managing hair loss. Several users have reported positive outcomes when pairing biotin with additional supplements such as vitamin C and lactic acid bacteria. For instance, one reviewer noted that after six months of this combined regimen, they observed thicker hair in previously sparse areas, indicating synergistic effects between the different supplements Read Review.
Conversely, some users have expressed that combining various supplements can yield mixed results. One user shared their experience with taking NAC and suggested that the combination might have led to an increase in hair loss at first, although there was eventual regrowth of lost hair Read Review. This suggests that while some combinations may enhance the effectiveness of the supplements in promoting hair health, others could create unintended side effects. As always, individual results will vary depending on overall health, diet, and specific hair care routines.
Based on user reviews, there appears to be a consensus that dosing of N Acetyl Cysteine (NAC) for treating hair loss varies significantly among individuals. One user highlighted their regimen of taking NAC at 500 to 600 mg alone, two to three times a year, along with vitamins and noted an overall increase in hair health post-regimen, even as they experienced increased hair loss initially Read Review. Other reviews did not specify exact dosages but mentioned positive effects related to hair loss when taking NAC in combination with other supplements like biotin and vitamin C, suggesting an integrated approach to hair care Read Review.
Users emphasized the importance of individual experimentation to find the right dose, as factors like existing health conditions, concurrent supplement intake, and personal body response can greatly influence outcomes. A few emphasized the need for a balanced intake of additional nutrients to support hair health, but no definitive “gold standard” dosage emerged from the reviews. Overall, while some users found efficacy in their dosages, others reported mixed results, indicating that personalized approaches may be necessary for effective use of NAC in combating hair loss.
9
Hair loss reduced
2 people found this helpful
I have been taking biotin for several weeks, which has significantly reduced my hair loss. I have more energy, and my mood has stabilised.
6
Thicker hair observed
15 people found this helpful
I've been taking biotin, vitamin C, and lactic acid bacteria. After six months, I've noticed thicker hair in areas affected by hair loss, which had previously been sparse.
7.5
Hair loss ceased
I started taking this product in early 2021, having envied my colleague. My hair loss has stopped, though I'm unsure how much credit it deserves, as I engage in various hair care practices.
7.5
Decreased hair loss
3 people found this helpful
I liked this product; it has helped with sputum discharge in chronic bronchitis, and as a bonus, my hair loss has decreased.
6
Hair regrowth noted
2 people found this helpful
I'm interested in products with a high degree of magical remodeling and a substantial amount of NAC (600mg per tablet), along with a balanced intake of selenium and molybdenum. I combine 500 to 600 mg of NAC alone two to three times yearly for detoxification over half a month to a month, taking vitamins immediately upon waking. I take them with vitamin C. After starting this regimen, I noted an increase in hair loss. If selenium is taken alongside other multivitamins and minerals, it might lead to excess. Fortunately, the hair that has fallen out is gradually growing back.
8
Selenium may aid hair loss treatments
Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study.
We conducted a thorough investigation into the effectiveness of a novel oral supplement containing selenium, among other ingredients, in addressing hair loss conditions like androgenetic alopecia (AGA) and telogen effluvium (TE). Our study involved 83 participants who were divided into two groups: one received the supplement alongside their prescribed treatments, while the other received only the treatments.
Over 12 weeks, we assessed the outcomes primarily through a global assessment score to see how much improvement, if any, participants experienced. Interestingly, we found that the supplement—rich in selenium, amino acids, and hydrolyzed collagen—enhanced the results for those undergoing anti-hair loss therapies.
In essence, the inclusion of selenium in this combination supplement appears to positively influence the effectiveness of standard treatments for hair loss. While our study was promising, it’s worth noting that deriving individual results for selenium alone is complicated since it was combined with other beneficial components.
8
Selenium aids hair loss in PCOS
Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome.
We conducted a randomized double-blind, placebo-controlled trial to explore how selenium supplementation may influence hair loss among women with polycystic ovary syndrome (PCOS). In the study, 64 women aged 18-40 received either 200 μg of selenium daily or a placebo for eight weeks.
After the treatment period, we noticed a significant improvement in hair-related issues for those taking selenium. Specifically, alopecia rates dropped from 40.6% in the selenium group to just 9.4% in the placebo group, showing a strong positive effect of the supplement on hair loss. Acne also improved, with a reduction from 46.9% to 12.5%.
Furthermore, women who took selenium supplements exhibited decreased levels of dehydroepiandrosterone (DHEA), hirsutism, and markers of inflammation and oxidative stress. However, it’s important to note that selenium did not show significant effects on some hormonal profiles and other biomarkers. Overall, our findings suggest that selenium can be beneficial for women with PCOS, particularly regarding hair loss and related symptoms.
We explored a novel approach to treat androgenetic alopecia (AGA) using microneedles that deliver selenium nanoparticles. The study designed a biocomposite patch to improve the environment around hair follicles by enhancing blood flow and reducing inflammation.
When tested on mice, this microneedle system showed promise in boosting hair density and enlarging hair follicles. However, while the results are encouraging, further research is needed to confirm its effectiveness in humans.
8
Selenium supplementation may help hair loss
Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy.
We examined how selenium supplementation influences hair loss in women undergoing chemotherapy for ovarian cancer. This study involved 31 patients who received 200 micrograms of selenium daily.
Over three months, we noticed significant improvements: hair loss decreased, alongside reductions in discomfort and fatigue. While selenium levels in patients' hair didn't increase markedly after the first month, serum levels rose significantly.
Ultimately, selenium appears beneficial as a supportive treatment in managing hair loss during chemotherapy.
References
Milani M, Colombo F. Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study. Skin Res Technol. 2023;29:e13381. doi:10.1111/srt.13381
Razavi M, Jamilian M, Kashan ZF, Heidar Z, Mohseni M, et al. Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome. Horm Metab Res. 2016;48:185. doi:10.1055/s-0035-1559604
Jing S, Liu Y, Wang B, Zhou H, Zhang H, et al. Microneedle-mediated hypoxic extracellular vesicle-encapsulated selenium nanoparticles delivery to treat androgenetic alopecia. J Control Release. 2025;381:113597. doi:10.1016/j.jconrel.2025.113597
Sieja K, Talerczyk M. Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy. Gynecol Oncol. 2004;93:320.